Tm4sf5^em2Jwnl
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tm4sf5^em2Jwnl
• Name: transmembrane 4 superfamily member 5; endonuclease-mediated mutation 2, Jung Weon Lee
• MGI ID: MGI:7425022
• Gene: Tm4sf5 Location: Chr11:70396100-70402009 bp, + strand Genetic Position: Chr11, 42.99 cM
• Alliance: Tm4sf5^em2Jwnl page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology deleted exons 3-5. (J:301194)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tm4sf5 Mutation: 12 strains or lines available

References

• Original: J:301194 Ryu J, et al., Differential TM4SF5-mediated SIRT1 modulation and metabolic signaling in nonalcoholic steatohepatitis progression. J Pathol. 2021 Jan;253(1):55-67
• All: 1 reference(s)