Ppargc1a^em1Ngwu
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ppargc1a^em1Ngwu
• Name: peroxisome proliferative activated receptor, gamma, coactivator 1 alpha; endonuclease-mediated mutation 1, Ning Wu
• MGI ID: MGI:7424949
• Synonyms: HisHA PGC1alpha KI
• Gene: Ppargc1a Location: Chr5:51611592-51725068 bp, - strand Genetic Position: Chr5, 27.02 cM, cytoband C1
• Alliance: Ppargc1a^em1Ngwu page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Epitope tag)
• Mutation: Insertion
• Mutation details: crRNA/tracrRNA duplex gRNA was designed to insert a C-terminal HisHA tag immediately upstream of the stop codon. (J:332404)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ppargc1a Mutation: 47 strains or lines available

References

• Original: J:332404 Lau KH, et al., PPARgamma and C/EBPalpha response to acute cold stress in brown adipose tissue. iScience. 2023 Jan 20;26(1):105848
• All: 1 reference(s)