Aim2^em1Bcgen
Endonuclease-mediated Allele Detail

Summary

• Symbol: Aim2^em1Bcgen
• Name: absent in melanoma 2; endonuclease-mediated mutation 1, Biocytogen LLC
• MGI ID: MGI:7423784
• Synonyms: AIM2^fl
• Gene: Aim2 Location: Chr1:173178445-173293606 bp, + strand Genetic Position: Chr1, 80.33 cM
• Alliance: Aim2^em1Bcgen page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Exons 5 was flanked by loxP sites using CRISPR/Cas9 technology. (J:332349)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Aim2 Mutation: 35 strains or lines available

References

• Original: J:332349 Ma C, et al., AIM2 controls microglial inflammation to prevent experimental autoimmune encephalomyelitis. J Exp Med. 2021 May 3;218(5)
• All: 2 reference(s)