Atf7ip^tm1.1Mand
Targeted Allele Detail

Summary

• Symbol: Atf7ip^tm1.1Mand
• Name: activating transcription factor 7 interacting protein; targeted mutation 1.1, Mark S Anderson
• MGI ID: MGI:7414388
• Gene: Atf7ip Location: Chr6:136495787-136587848 bp, + strand Genetic Position: Chr6, 66.59 cM, cytoband G1
• Alliance: Atf7ip^tm1.1Mand page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:282560
• Parent Cell Line: JM8A3.N1 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exon 2 was floxed and an FRT-flanked neo cassette was inserted via homologous recombination. Flp mediated recombination removed the neo cassette. (J:282560)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atf7ip Mutation: 326 strains or lines available

References

• Original: J:282560 Sin JH, et al., The epigenetic regulator ATF7ip inhibits Il2 expression, regulating Th17 responses. J Exp Med. 2019 Sep 2;216(9):2024-2037
• All: 3 reference(s)