Gja1^em4Smoc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gja1^em4Smoc
• Name: gap junction protein, alpha 1; endonuclease-mediated mutation 4, Shanghai Model Organisms Center
• MGI ID: MGI:7414354
• Synonyms: Cx43-BFP-GFP
• Gene: Gja1 Location: Chr10:56253297-56266519 bp, + strand Genetic Position: Chr10, 28.64 cM
• Alliance: Gja1^em4Smoc page

Mutation origin

• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Endonuclease-mediated (Reporter)
• Mutation: Insertion
• Mutation details: CRISPR-targeting inserted a loxP site, tagBFP reporter gene, WPRE, polyA signal, loxP, EGFP reporter gene, WPRE, and polyA sequence at the start codon site. (J:330697)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gja1 Mutation: 62 strains or lines available

References

• Original: J:330697 Liu S, et al., Expression of connexin 43 protein in cardiomyocytes of heart failure mouse model. Front Cardiovasc Med. 2022;9:1028558
• All: 1 reference(s)