Sirt7^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Sirt7^em1Cya
• Name: sirtuin 7; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:7414301
• Gene: Sirt7 Location: Chr11:120509197-120515840 bp, - strand Genetic Position: Chr11, 84.34 cM
• Alliance: Sirt7^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Not Specified
• CRISPR-targeting generated a null allele. (J:330780)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sirt7 Mutation: 21 strains or lines available

References

• Original: J:330780 Liu Z, et al., SIRT7 couples light-driven body temperature cues to hepatic circadian phase coherence and gluconeogenesis. Nat Metab. 2019 Nov;1(11):1141-1156
• All: 1 reference(s)