Acp1^em1Mrl
Endonuclease-mediated Allele Detail

Summary

• Symbol: Acp1^em1Mrl
• Name: acid phosphatase 1, soluble; endonuclease-mediated mutation 1, Merck Research Laboratory
• MGI ID: MGI:7414292
• Gene: Acp1 Location: Chr12:30943325-30961588 bp, - strand Genetic Position: Chr12, 13.0 cM
• Alliance: Acp1^em1Mrl page

Mutation origin

• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted exons 2 through 5. (J:330782)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Acp1 Mutation: 13 strains or lines available

References

• Original: J:330782 Jensen-Cody S, et al., Loss of low-molecular-weight protein tyrosine phosphatase shows limited improvement in glucose tolerance but causes mild cardiac hypertrophy in mice. Am J Physiol Endocrinol Metab. 2022 Jun 1;322(6):E517-E527
• All: 1 reference(s)