Cic^em1Leey
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cic^em1Leey
• Name: capicua transcriptional repressor; endonuclease-mediated mutation 1, Yoontae Lee
• MGI ID: MGI:7414092
• Synonyms: Cic^FLAG
• Gene: Cic Location: Chr7:24967129-24993584 bp, + strand Genetic Position: Chr7, 13.73 cM
• Alliance: Cic^em1Leey page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Epitope tag)
• Mutation: Insertion
• CRISPR-cas9 mediated recombination inserted a 3X-FLAG tag at the 3' end of the open reading frame. (J:295778)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cic Mutation: 99 strains or lines available

References

• Original: J:295778 Park S, et al., The Capicua/ETS Translocation Variant 5 Axis Regulates Liver-Resident Memory CD8(+) T-Cell Development and the Pathogenesis of Liver Injury. Hepatology. 2019 Jul;70(1):358-371
• All: 3 reference(s)