Cd40lg^em2(srta)Vic
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cd40lg^em2(srta)Vic
• Name: CD40 ligand; endonuclease-mediated mutation 2, Gabriel Victora
• MGI ID: MGI:7414033
• Synonyms: Cd40lg^SrtA2
• Gene: Cd40lg Location: ChrX:56257503-56269402 bp, + strand Genetic Position: ChrX, 31.21 cM
• Alliance: Cd40lg^em2(srta)Vic page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Epitope tag)
• Mutation: Insertion
• Mutation details: CRISPR/cas9 genome editing is used sgRNA (GAGTTGGCTTCTCATCTTT) designed to insert a Staphylococcus aureus transpeptidase sortase A (SrtA) tag fused at the 3' end of the gene. (J:332294)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cd40lg Mutation: 14 strains or lines available

References

• Original: J:332294 Chudnovskiy A, et al., Proximity-dependent labeling identifies dendritic cells that prime the antitumor CD4+ T cell response. bioRxiv. 2022
• All: 2 reference(s)