Ckb^em1Kazl
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ckb^em1Kazl
• Name: creatine kinase, brain; endonuclease-mediated mutation 1, Lawrence Kazak
• MGI ID: MGI:7414006
• Synonyms: Ckb^fl
• Gene: Ckb Location: Chr12:111635795-111638772 bp, - strand Genetic Position: Chr12, 61.09 cM
• Alliance: Ckb^em1Kazl page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• CRISPR-cas9 mediated recombination inserted loxP sites around exon 3. (J:305293)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ckb Mutation: 27 strains or lines available

References

• Original: J:305293 Rahbani JF, et al., Creatine kinase B controls futile creatine cycling in thermogenic fat. Nature. 2021 Feb;590(7846):480-485
• All: 5 reference(s)