Rnf31^em1Xlin
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rnf31^em1Xlin
• Name: ring finger protein 31; endonuclease-mediated mutation 1, Xin Lin
• MGI ID: MGI:7413941
• Synonyms: Hoip^flox
• Gene: Rnf31 Location: Chr14:55829199-55841131 bp, + strand Genetic Position: Chr14, 28.19 cM
• Alliance: Rnf31^em1Xlin page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Mutation details: CRISPR - cas9 mediated recombination using guide RNAs introduced loxP sites in intron 5 and intron 11. (J:263328)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rnf31 Mutation: 48 strains or lines available

References

• Original: J:263328 Tang Y, et al., RNF31 Regulates Skin Homeostasis by Protecting Epidermal Keratinocytes from Cell Death. J Immunol. 2018 Jun 15;200(12):4117-4124
• All: 3 reference(s)