Slc18a1^em4Mkwt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Slc18a1^em4Mkwt
• Name: solute carrier family 18 (vesicular monoamine), member 1; endonuclease-mediated mutation 4, Masakado Kawata
• MGI ID: MGI:7413204
• Synonyms: Vmat1^3xHA
• Gene: Slc18a1 Location: Chr8:69490363-69541887 bp, - strand Genetic Position: Chr8, 33.88 cM
• Alliance: Slc18a1^em4Mkwt page

Mutation origin

• Strain of Origin: (C57BL/6NCrSlc x C3H/HeSlc)F1

Mutation description

• Allele Type: Endonuclease-mediated (Epitope tag)
• Mutation: Insertion
• CRISPR-targeting exon 17 inserted a triple HA tag at the STOP codon. (J:330805)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc18a1 Mutation: 22 strains or lines available

References

• Original: J:330805 Sato DX, et al., Humanized substitutions of Vmat1 in mice alter amygdala-dependent behaviors associated with the evolution of anxiety. iScience. 2022 Aug 19;25(8):104800
• All: 1 reference(s)