Ubap2l^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ubap2l^em1Cya
• Name: ubiquitin-associated protein 2-like; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:7413184
• Gene: Ubap2l Location: Chr3:89907447-89959935 bp, - strand Genetic Position: Chr3, 39.19 cM, cytoband F2
• Alliance: Ubap2l^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-cas9 mediated recombination using guide RNAs targeting introns 2 and 6 created a deletion spanning exons 3 through 6. (J:327596)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ubap2l Mutation: 71 strains or lines available

References

• Original: J:327596 Jia X, et al., De novo variants in genes regulating stress granule assembly associate with neurodevelopmental disorders. Sci Adv. 2022 Aug 19;8(33):eabo7112
• All: 1 reference(s)