Idh1^em1Smoc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Idh1^em1Smoc
• Name: isocitrate dehydrogenase 1 (NADP+), soluble; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:7413098
• Gene: Idh1 Location: Chr1:65197775-65225638 bp, - strand Genetic Position: Chr1, 32.91 cM
• Alliance: Idh1^em1Smoc page

Mutation origin

• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR-targeting floxed exon 3. (J:332203)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Idh1 Mutation: 40 strains or lines available

References

• Original: J:332203 Zhao Q, Mutant IDH1 attenuates hepatic lipogenesis through PTEN dependent pathway. Biochem Biophys Res Commun. 2022 Dec 31;637:254-258
• All: 1 reference(s)