Slc4a8^em1Sole
Endonuclease-mediated Allele Detail

Summary

• Symbol: Slc4a8^em1Sole
• Name: solute carrier family 4 (anion exchanger), member 8; endonuclease-mediated mutation 1, Manoocher Soleimani
• MGI ID: MGI:7413033
• Gene: Slc4a8 Location: Chr15:100659628-100721849 bp, + strand Genetic Position: Chr15, 56.39 cM, cytoband F3
• Alliance: Slc4a8^em1Sole page

Mutation origin

• Strain of Origin: C57

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-cas9 mediated recombination using guide RNAs targeting exons 3 and 4 created a 40 bp deletion in exon 3. (J:328865)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc4a8 Mutation: 55 strains or lines available

References

• Original: J:328865 Xu J, et al., Slc4a8 in the Kidney: Expression, Subcellular Localization and Role in Salt Reabsorption. Cell Physiol Biochem. 2018;50(4):1361-1375
• All: 1 reference(s)