Bach2^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Bach2^em1Cya
• Name: BTB and CNC homology, basic leucine zipper transcription factor 2; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:7411303
• Synonyms: Bach2^em1Cya
• Gene: Bach2 Location: Chr4:32238804-32586108 bp, + strand Genetic Position: Chr4, 14.02 cM, cytoband A4
• Alliance: Bach2^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of exon 2 generated a null allele. (J:330837)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Bach2 Mutation: 43 strains or lines available

References

• Original: J:330837 Jiang X, et al., Protections of transcription factor BACH2 and natural product myricetin against pathological cardiac hypertrophy and dysfunction. Front Physiol. 2022;13:971424
• All: 1 reference(s)