Pim2^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pim2^em1Cya
• Name: Pim2, proto-oncogene, serine/threonine kinase; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:7411274
• Gene: Pim2 Location: ChrX:7744545-7749671 bp, + strand Genetic Position: ChrX, 3.55 cM
• Alliance: Pim2^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Not Specified
• CRISPR-targeting generated a null allele. (J:330851)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pim2 Mutation: 6 strains or lines available

References

• Original: J:330851 Lu C, et al., Phosphorylation of PFKFB4 by PIM2 promotes anaerobic glycolysis and cell proliferation in endometriosis. Cell Death Dis. 2022 Sep 15;13(9):790
• All: 1 reference(s)