Tn(sb-SBlac)15.196554Fsp
Transgene Detail

Summary

• Symbol: Tn(sb-SBlac)15.196554Fsp
• Name: transposon insertion 15.196554, Francois Spitz
• MGI ID: MGI:7411172
• Synonyms: SB-196554
• Transgene: Tn(sb-SBlac)15.196554Fsp Location: unknown Genetic Position: Chr15, Syntenic
• Alliance: Tn(sb-SBlac)15.196554Fsp page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Transposon induced (Conditional ready, Reporter)
• Mutation: Transposon insertion
• Mutation details: Re-mobilization of the transposon from Tn(sb-SBlac)15.179039Fsp transgenic mice with Sleeping Beauty transposase from an unidentified line of TgTn(sb-SBlac)15Fsp transgenic mice results in the integration of the transposon into chromosome 15 between Myc and Gsdmc at chr15:63564154-63564155 (GRCm39) in forward orientation. The transposon consists of a Sleeping Beauty transposon inverted repeat, loxP site, human beta-globin HBB minimal promoter, the lacZ beta-galactosidase reporter gene, SV40 poly(A) signal sequence, and a Sleeping Beauty transposon direct repeat. (J:257739)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:257739 Bahr C, et al., A Myc enhancer cluster regulates normal and leukaemic haematopoietic stem cell hierarchies. Nature. 2018 Jan 25;553(7689):515-520
• All: 1 reference(s)