Rabep2^em1Dmar
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rabep2^em1Dmar
• Name: rabaptin, RAB GTPase binding effector protein 2; endonuclease-mediated mutation 1, Douglas Marchuk
• MGI ID: MGI:7408531
• Gene: Rabep2 Location: Chr7:126027596-126045079 bp, + strand Genetic Position: Chr7, 69.03 cM
• Alliance: Rabep2^em1Dmar page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of exon 3 deleted 55 bp. (J:330882)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rabep2 Mutation: 40 strains or lines available

References

• Original: J:330882 Lee HK, et al., A cross-species approach using an in vivo evaluation platform in mice demonstrates that sequence variation in human RABEP2 modulates ischemic stroke outcomes. Am J Hum Genet. 2022 Oct 6;109(10):1814-1827
• All: 1 reference(s)