Hsd11b1^em1Rttr
Endonuclease-mediated Allele Detail

Summary

• Symbol: Hsd11b1^em1Rttr
• Name: hydroxysteroid 11-beta dehydrogenase 1; endonuclease-mediated mutation 1, Guy Rutter
• MGI ID: MGI:7408413
• Gene: Hsd11b1 Location: Chr1:192903917-192946345 bp, - strand Genetic Position: Chr1, 97.67 cM
• Alliance: Hsd11b1^em1Rttr page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted exon 1. (J:330886)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hsd11b1 Mutation: 29 strains or lines available

References

• Original: J:330886 Akalestou E, et al., Vertical sleeve gastrectomy normalizes circulating glucocorticoid levels and lowers glucocorticoid action tissue-selectively in mice. Front Endocrinol (Lausanne). 2022;13:1020576
• All: 1 reference(s)