Slc43a2^tm1.1Verf
Targeted Allele Detail

Summary

• Symbol: Slc43a2^tm1.1Verf
• Name: solute carrier family 43, member 2; targeted mutation 1.1, Francois Verrey
• MGI ID: MGI:7408328
• Synonyms: LAT4^fl
• Gene: Slc43a2 Location: Chr11:75422520-75468401 bp, + strand Genetic Position: Chr11, 45.92 cM
• Alliance: Slc43a2^tm1.1Verf page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:329575
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exon 5 was floxed and an FRT-flanked neo cassette was inserted via homologous recombination. Flp-mediated recombination removed the neo cassette. (J:329575)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc43a2 Mutation: 29 strains or lines available

References

• Original: J:329575 Rajendran A, et al., Tissue-specific deletion of mouse basolateral uniporter LAT4 (Slc43a2) reveals its crucial role in small intestine and kidney amino acid transport. J Physiol. 2020 Nov;598(22):5109-5132
• All: 3 reference(s)