Mavs^em1Mpa
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mavs^em1Mpa
• Name: mitochondrial antiviral signaling protein; endonuclease-mediated mutation 1, Manolis Pasparakis
• MGI ID: MGI:7408327
• Gene: Mavs Location: Chr2:131075983-131089945 bp, + strand Genetic Position: Chr2, 63.3 cM
• Alliance: Mavs^em1Mpa page

Mutation origin

• Strain of Origin: C57BL/6NRj

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted exons 3 through 6. (J:331944)

Expression

In Mice Carrying this Mutation:

2 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mavs Mutation: 38 strains or lines available

References

• Original: J:331944 Jiao H, et al., ADAR1 averts fatal type I interferon induction by ZBP1. Nature. 2022 Jul;607(7920):776-783
• All: 1 reference(s)