Igs49^em2Mam
Endonuclease-mediated Allele Detail

Summary

• Symbol: Igs49^em2Mam
• Name: intergenic site 49; endonuclease-mediated mutation 2, Lothar Hennighausen
• MGI ID: MGI:7408226
• Synonyms: GAS^E2-R3
• Gene: Igs49 Location: unknown Genetic Position: Chr11, Syntenic
• Alliance: Igs49^em2Mam page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Modified regulatory region)
• Mutation: Intergenic deletion
• Mutation details: CRISPR-targeting in zygotes containing Rr328^em4Mam deleted 800 bp including Rr330 through 600 bp upstream of Ramp3. (J:266979)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Igs49 Mutation: 0 strains or lines available

References

• Original: J:266979 Lee HK, et al., Progressing super-enhancer landscape during mammary differentiation controls tissue-specific gene regulation. Nucleic Acids Res. 2018 Nov 16;46(20):10796-10809
• All: 1 reference(s)