Inpp5k^tm1Cmit
Targeted Allele Detail

Summary

• Symbol: Inpp5k^tm1Cmit
• Name: inositol polyphosphate 5-phosphatase K; targeted mutation 1, Christina A Mitchell
• MGI ID: MGI:7408223
• Synonyms: Inpp5k^fl
• Gene: Inpp5k Location: Chr11:75521814-75539697 bp, + strand Genetic Position: Chr11, 45.92 cM
• Alliance: Inpp5k^tm1Cmit page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:313530
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Exon 8 was flanked by loxP sites. (J:313530)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Inpp5k Mutation: 32 strains or lines available

References

• Original: J:313530 McGrath MJ, et al., Defective lysosome reformation during autophagy causes skeletal muscle disease. J Clin Invest. 2021 Jan 4;131(1)
• All: 2 reference(s)