Kdm2a^tm1Lij
Targeted Allele Detail

Summary

• Symbol: Kdm2a^tm1Lij
• Name: lysine (K)-specific demethylase 2A; targeted mutation 1, Jian Li
• MGI ID: MGI:7408206
• Synonyms: Kdm2a^flox
• Gene: Kdm2a Location: Chr19:4366172-4448749 bp, - strand Genetic Position: Chr19, 4.01 cM
• Alliance: Kdm2a^tm1Lij page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:330905
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The targeting construct flanked exon 6 with a loxP site and a Rox site flanked neomycin resistance cassette with a 3' loxP site. (J:330905)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kdm2a Mutation: 104 strains or lines available

References

• Original: J:330905 Xiong X, et al., Oocyte-Specific Knockout of Histone Lysine Demethylase KDM2a Compromises Fertility by Blocking the Development of Follicles and Oocytes. Int J Mol Sci. 2022 Oct 9;23(19)
• All: 1 reference(s)