Xirp2^em3Pgg
Endonuclease-mediated Allele Detail

Summary

• Symbol: Xirp2^em3Pgg
• Name: xin actin-binding repeat containing 2; endonuclease-mediated mutation 3, Peter G Gillespie
• MGI ID: MGI:7408069
• Gene: Xirp2 Location: Chr2:67276343-67356964 bp, + strand Genetic Position: Chr2, 39.31 cM
• Alliance: Xirp2^em3Pgg page

Mutation origin

• Strain of Origin: (C57BL/6 x SJL)F1

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of exon 2 deleted 17 bp. (J:219773)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Xirp2 Mutation: 163 strains or lines available

References

• Original: J:219773 Francis SP, et al., A short splice form of Xin-actin binding repeat containing 2 (XIRP2) lacking the Xin repeats is required for maintenance of stereocilia morphology and hearing function. J Neurosci. 2015 Feb 4;35(5):1999-2014
• All: 1 reference(s)