Eedtm1d(EUCOMM)Wtsi
Targeted Allele Detail
|
Symbol: |
Eedtm1d(EUCOMM)Wtsi |
Name: |
embryonic ectoderm development; targeted mutation 1d, Wellcome Trust Sanger Institute |
MGI ID: |
MGI:7398609 |
Gene: |
Eed Location: Chr7:89603862-89630184 bp, - strand Genetic Position: Chr7, 50.42 cM
|
Alliance: |
Eedtm1d(EUCOMM)Wtsi page
|
IMPC: |
Eed gene page |
|
Germline Transmission: |
Earliest citation of germline transmission:
J:275851
|
Parent Cell Line: |
JM8.F6 (ES Cell)
|
Strain of Origin: |
C57BL/6N
|
Project Collection: |
EUCOMM
|
|
Allele Type: |
|
Targeted (Null/knockout) |
Mutations: |
|
Insertion, Intragenic deletion
|
|
|
Mutation details: The L1L2_gt1 cassette was inserted at position 89616630 of Chromosome 7 upstream of the exon 7 (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. An additional loxP site is inserted downstream of the exon 7 at position 89617432. Exon 7 was thus flanked by loxP sites. A "conditional ready" (floxed) allele was created by flp mediated recombination. Cre-mediated recombination removed the floxed exon. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml.
(J:275851)
|
|
|
|
Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
Carrying any Eed Mutation: |
116 strains or lines available
|
|
Original: |
J:275851 Harris C, et al., Conversion of random X-inactivation to imprinted X-inactivation by maternal PRC2. Elife. 2019 Apr 2;8:e44258 |
All: |
1 reference(s) |
|