Ovol2^em1Btlr
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ovol2^em1Btlr
• Name: ovo like zinc finger 2; endonuclease-mediated mutation 1, Bruce Beutler
• MGI ID: MGI:7398549
• Gene: Ovol2 Location: Chr2:144147095-144174000 bp, - strand Genetic Position: Chr2, 70.99 cM, cytoband H1
• Alliance: Ovol2^em1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Not Specified
• CRISPR-targeting generated a null allele. (J:330954)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ovol2 Mutation: 23 strains or lines available

References

• Original: J:330954 Zhang Z, et al., Obesity caused by an OVOL2 mutation reveals dual roles of OVOL2 in promoting thermogenesis and limiting white adipogenesis. Cell Metab. 2022 Nov 1;34(11):1860-1874.e4
• All: 1 reference(s)