Rab27b^em1Bcgen
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rab27b^em1Bcgen
• Name: RAB27B, member RAS oncogene family; endonuclease-mediated mutation 1, Biocytogen LLC
• MGI ID: MGI:7388668
• Synonyms: Rab27b^fl
• Gene: Rab27b Location: Chr18:70112202-70274676 bp, - strand Genetic Position: Chr18, 43.89 cM
• Alliance: Rab27b^em1Bcgen page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR/Cas9 technology inserted loxP sites flanking exons 3 to 4. (J:331542)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rab27b Mutation: 28 strains or lines available

References

• Original: J:331542 Bauer KM, et al., CD11c+ myeloid cell exosomes reduce intestinal inflammation during colitis. JCI Insight. 2022 Oct 10;7(19)
• All: 2 reference(s)