Slc16a2^em2Agfz
Endonuclease-mediated Allele Detail

Summary

• Symbol: Slc16a2^em2Agfz
• Name: solute carrier family 16 (monocarboxylic acid transporters), member 2; endonuclease-mediated mutation 2, Ana Guadano-Ferraz
• MGI ID: MGI:7388562
• Synonyms: Mct8^P253L
• Gene: Slc16a2 Location: ChrX:102741020-102865589 bp, - strand Genetic Position: ChrX, 46.29 cM
• Alliance: Slc16a2^em2Agfz page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Single point mutation
• Mutation details: CRISPR-targeting the mutation that results in the amino acid substitution of proline with leucine at position 253 (P253L). (J:330968)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc16a2 Mutation: 13 strains or lines available

References

• Original: J:330968 Valcarcel-Hernandez V, et al., A CRISPR/Cas9-engineered avatar mouse model of monocarboxylate transporter 8 deficiency displays distinct neurological alterations. Neurobiol Dis. 2022 Nov;174:105896
• All: 1 reference(s)