Sema4a^em1Slp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Sema4a^em1Slp
• Name: sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A; endonuclease-mediated mutation 1, Samuel L Pfaff
• MGI ID: MGI:7388560
• Gene: Sema4a Location: Chr3:88343266-88368489 bp, - strand Genetic Position: Chr3, 38.83 cM
• Alliance: Sema4a^em1Slp page

Mutation origin

• Strain of Origin: (BALB/cByKh x C57BL/6ByKh)F1

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted exon 2 through part of exon 3. (J:330969)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sema4a Mutation: 41 strains or lines available

References

• Original: J:330969 Martins LF, et al., Motor neurons use push-pull signals to direct vascular remodeling critical for their connectivity. Neuron. 2022 Oct 7
• All: 2 reference(s)