Mir10b^em1Jfka
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mir10b^em1Jfka
• Name: microRNA 10b; endonuclease-mediated mutation 1, Jiefang Kang
• MGI ID: MGI:7388470
• Gene: Mir10b Location: Chr2:74556414-74556481 bp, + strand Genetic Position: Chr2, 44.13 cM
• Alliance: Mir10b^em1Jfka page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology generated a knock-out allele. (J:331504)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mir10b Mutation: 3 strains or lines available

References

• Original: J:331504 Zhao K, et al., Deficiency of microRNA-10b promotes DSS-induced inflammatory response via impairing intestinal barrier function. Biochem Biophys Res Commun. 2022 Dec 25;636(Pt 2):48-54
• All: 1 reference(s)