Xpo7^tm1.1Dglh
Targeted Allele Detail

Summary

• Symbol: Xpo7^tm1.1Dglh
• Name: exportin 7; targeted mutation 1.1, Dirk Gorlich
• MGI ID: MGI:7388266
• Synonyms: Xpo7 A^-
• Gene: Xpo7 Location: Chr14:70899566-71004075 bp, - strand Genetic Position: Chr14, 36.44 cM, cytoband D1
• Alliance: Xpo7^tm1.1Dglh page
• IMPC: Xpo7 gene page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:331429
• Parent Cell Line: MPI-II (ES Cell)
• Strain of Origin: 129S2/SvPas
• Project Collection: KOMP-CSD

Mutation description

• Allele Type: Targeted (Modified isoform(s))
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting construct floxed exon IA. Cre-mediated recombination removed the exon preventing the expression of isoform A. (J:331429)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Xpo7 Mutation: 82 strains or lines available

References

• Original: J:331429 Modepalli S, et al., An In Vivo Model for Elucidating the Role of an Erythroid-Specific Isoform of Nuclear Export Protein Exportin 7 (Xpo7) in Murine Erythropoiesis. Exp Hematol. 2022 Aug 13
• All: 1 reference(s)