Faf1^em1Jye
Endonuclease-mediated Allele Detail

Summary

• Symbol: Faf1^em1Jye
• Name: Fas-associated factor 1; endonuclease-mediated mutation 1, Jin Ye
• MGI ID: MGI:7388146
• Synonyms: Faf1^f
• Gene: Faf1 Location: Chr4:109533873-109821157 bp, + strand Genetic Position: Chr4, 51.33 cM, cytoband C6
• Alliance: Faf1^em1Jye page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR/Cas9 technology inserted loxP sites flanking exon 3. (J:331364)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Faf1 Mutation: 96 strains or lines available

References

• Original: J:331364 Cui S, et al., FAF1 blocks ferroptosis by inhibiting peroxidation of polyunsaturated fatty acids. Proc Natl Acad Sci U S A. 2022 Apr 26;119(17):e2107189119
• All: 1 reference(s)