Acot2^tm1.2Elst
Targeted Allele Detail

Summary

• Symbol: Acot2^tm1.2Elst
• Name: acyl-CoA thioesterase 2; targeted mutation 1.2, Erin L Seifert
• MGI ID: MGI:7386916
• Gene: Acot2 Location: Chr12:84034635-84040647 bp, + strand Genetic Position: Chr12, 38.99 cM, cytoband D3
• Alliance: Acot2^tm1.2Elst page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:282877
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting construct floxed exon 2. Flp-mediated recombination removed the selection cassette. Cre-mediated recombiantion removed exon 2. (J:282877)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Acot2 Mutation: 18 strains or lines available

References

• Original: J:282877 Bekeova C, et al., Multiple mitochondrial thioesterases have distinct tissue and substrate specificity and CoA regulation, suggesting unique functional roles. J Biol Chem. 2019 Dec 13;294(50):19034-19047
• All: 1 reference(s)