Prss3b^tm1Aksj
Targeted Allele Detail

Summary

• Symbol: Prss3b^tm1Aksj
• Name: serine protease 3B; targeted mutation 1, Ashok Saluja
• MGI ID: MGI:7385083
• Gene: Prss3b Location: Chr6:41007202-41012443 bp, - strand Genetic Position: Chr6, 19.1 cM
• Alliance: Prss3b^tm1Aksj page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:330333
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S7/SvEvBrd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• The targeting construct replaced the gene with a neomycin resistance cassette. (J:330333)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prss3b Mutation: 24 strains or lines available

Notes

ES cells = MK6 (129S7/SvEvBrd)

References

• Original: J:330333 Dawra R, et al., Intra-acinar trypsinogen activation mediates early stages of pancreatic injury but not inflammation in mice with acute pancreatitis. Gastroenterology. 2011 Dec;141(6):2210-2217.e2
• All: 2 reference(s)