Ddc^em1Nkn
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ddc^em1Nkn
• Name: dopa decarboxylase; endonuclease-mediated mutation 1, Toru Nakano
• MGI ID: MGI:7385033
• Synonyms: Ddc^em1(hKO1)Nkn
• Gene: Ddc Location: Chr11:11764101-11848144 bp, - strand Genetic Position: Chr11, 7.09 cM, cytoband A1-A4
• Alliance: Ddc^em1Nkn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:332239
• Parent Cell Line: G4 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6NCrl)F1

Mutation description

• Allele Type: Endonuclease-mediated (Reporter)
• Mutation: Insertion
• Mutation details: CRISPR-targeting inserted into exon 15 a P2A sequence, humanized Kusabira-Orange 1 reporter cassette, and floxed selection cassette. (J:332239)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ddc Mutation: 127 strains or lines available

References

• Original: J:332239 Sheng KY, et al., A region-dependent allele-biased expression of Dopa decarboxylase in mouse brain. Front Cell Dev Biol. 2022;10:1078927
• All: 1 reference(s)