Creg1^em1Shli
Endonuclease-mediated Allele Detail

Summary

• Symbol: Creg1^em1Shli
• Name: cellular repressor of E1A-stimulated genes 1; endonuclease-mediated mutation 1, Shaohua Li
• MGI ID: MGI:7384603
• Synonyms: Creg1^fl
• Gene: Creg1 Location: Chr1:165591327-165602878 bp, + strand Genetic Position: Chr1, 73.11 cM
• Alliance: Creg1^em1Shli page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: CRISPR/Cas9 technology inserted loxP sites to flank exons 1 to 3, which encode the entire open reading frame. (J:317416)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Creg1 Mutation: 9 strains or lines available

References

• Original: J:317416 Liu J, et al., CREG1 promotes lysosomal biogenesis and function. Autophagy. 2021 Dec;17(12):4249-4265
• All: 1 reference(s)