Gt(ROSA)26Sor^{tm1(CAG-G-CaMP9a,-R-CaMP2)Hbto}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(CAG-G-CaMP9a,-R-CaMP2)Hbto}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Haruhiko Bito
• MGI ID: MGI:7384596
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(CAG-G-CaMP9a,-R-CaMP2)Hbto} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:330745
• Parent Cell Line: RENKA (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Conditional ready, Reporter)
• Mutation: Insertion
• Mutation details: G-CaMP9a and R-CaMP2 reporter mice under the control of Flp/FRT and Cre/loxP recombination, respectively. R-CaMP2 expression can be regulated by tTA/rtTA, but its expression is relatively weak. (J:330745)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1089 strains or lines available

References

• Original: J:330745 Sakamoto M, et al., A Flp-dependent G-CaMP9a transgenic mouse for neuronal imaging in vivo. Cell Rep Methods. 2022;2(2):100168
• All: 2 reference(s)