Cdkn2a^em1Matsu
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cdkn2a^em1Matsu
• Name: cyclin dependent kinase inhibitor 2A; endonuclease-mediated mutation 1, Makoto Matsuyama
• MGI ID: MGI:7384582
• Gene: Cdkn2a Location: Chr4:89192710-89212856 bp, - strand Genetic Position: Chr4, 42.15 cM, cytoband C3-C6
• Alliance: Cdkn2a^em1Matsu page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Insertion
• CRISPR-targeting inserted a stop codon in exon 3. (J:284820)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Cdkn2a Mutation: 59 strains or lines available

References

• Original: J:284820 Koyano T, et al., The p21 dependent G2 arrest of the cell cycle in epithelial tubular cells links to the early stage of renal fibrosis. Sci Rep. 2019 Aug 19;9(1):12059
• All: 1 reference(s)