Cdkn1a^em1Matsu
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cdkn1a^em1Matsu
• Name: cyclin dependent kinase inhibitor 1A; endonuclease-mediated mutation 1, Makoto Matsuyama
• MGI ID: MGI:7384581
• Gene: Cdkn1a Location: Chr17:29309953-29319696 bp, + strand Genetic Position: Chr17, 15.12 cM
• Alliance: Cdkn1a^em1Matsu page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Duplication
• CRISPR-targeting inserted a stop codon exon 2. (J:284820)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Cdkn1a Mutation: 63 strains or lines available

References

• Original: J:284820 Koyano T, et al., The p21 dependent G2 arrest of the cell cycle in epithelial tubular cells links to the early stage of renal fibrosis. Sci Rep. 2019 Aug 19;9(1):12059
• All: 1 reference(s)