Tg(Adipoq-NPPC)HNcvcb
Transgene Detail

Summary

• Symbol: Tg(Adipoq-NPPC)HNcvcb
• Name: transgene insertion H, National Cerebral and Cardiovascular Center Research Institute
• MGI ID: MGI:7384424
• Synonyms: A-CNP Tg
• Transgene: Tg(Adipoq-NPPC)HNcvcb Location: unknown
• Alliance: Tg(Adipoq-NPPC)HNcvcb page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Adipoq-NPPC)HNcvcb expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  NPPC (4880)

  Nppc	(MGI:97369)

• Mutation details: The mouse promoter drives adipose-specific expression of the human gene. Line H has more transgene copies than line 1. (J:262658)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:262658 Bae CR, et al., Adipocyte-specific expression of C-type natriuretic peptide suppresses lipid metabolism and adipocyte hypertrophy in adipose tissues in mice fed high-fat diet. Sci Rep. 2018 Feb 1;8(1):2093
• All: 1 reference(s)