Mycl^em2Yasu
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mycl^em2Yasu
• Name: Mycl proto-oncogene, bHLH transcription factor; endonuclease-mediated mutation 2, Yasuhiro Yamada
• MGI ID: MGI:7384328
• Gene: Mycl Location: Chr4:122889445-122896278 bp, + strand Genetic Position: Chr4, 57.36 cM
• Alliance: Mycl^em2Yasu page

Mutation origin

• Strain of Origin: (C57BL/6J x 129S4/SvJae)F1

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted a portion of exon 1. (J:330715)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mycl Mutation: 17 strains or lines available

References

• Original: J:330715 Hirano M, et al., MYCL-mediated reprogramming expands pancreatic insulin-producing cells. Nat Metab. 2022;4(2):254-268
• All: 1 reference(s)