Tg(Prnp-TARDBP)1Koya
Transgene Detail

Summary

• Symbol: Tg(Prnp-TARDBP)1Koya
• Name: transgene insertion 1, Koji Yamanaka
• MGI ID: MGI:7382830
• Transgene: Tg(Prnp-TARDBP)1Koya Location: unknown
• Alliance: Tg(Prnp-TARDBP)1Koya page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Prnp-TARDBP)1Koya expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  TARDBP (23435)

  Tardbp

  (MGI:2387629)

• Mutation details: Transgenic mice expressing human wild-type TARDBP protein with 3x FLAG tag at C-terminal under the control of mouse Prnp promoter. (J:265116)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:265116 Tsuiji H, et al., TDP-43 accelerates age-dependent degeneration of interneurons. Sci Rep. 2017 Nov 2;7(1):14972
• All: 1 reference(s)