Ddit4^em1Ymk
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ddit4^em1Ymk
• Name: DNA-damage-inducible transcript 4; endonuclease-mediated mutation 1, Young-Myeong Kim
• MGI ID: MGI:7382786
• Synonyms: Redd1^-
• Gene: Ddit4 Location: Chr10:59785497-59787592 bp, - strand Genetic Position: Chr10, 29.66 cM, cytoband B3
• Alliance: Ddit4^em1Ymk page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Using CRISPR/Cas9 in C57BL/6 zygotes, a null allele was generated. (J:330638)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ddit4 Mutation: 20 strains or lines available

References

• Original: J:330638 Lee DK, et al., REDD1 promotes obesity-induced metabolic dysfunction via atypical NF-kappaB activation. Nat Commun. 2022 Oct 22;13(1):6303
• All: 1 reference(s)