Ramp1^tm1.2Tsuj
Targeted Allele Detail

Summary

• Symbol: Ramp1^tm1.2Tsuj
• Name: receptor (calcitonin) activity modifying protein 1; targeted mutation 1.2, Kazutake Tsujikawa
• MGI ID: MGI:7382757
• Gene: Ramp1 Location: Chr1:91107544-91152918 bp, + strand Genetic Position: Chr1, 46.08 cM
• Alliance: Ramp1^tm1.2Tsuj page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:125974
• Parent Cell Line: D3 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• A pair of loxP flanks exon 2. Cre-mediated recombination removed the selection cassette. (J:125974)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ramp1 Mutation: 19 strains or lines available

References

• Original: J:125974 Tsujikawa K, et al., Hypertension and dysregulated proinflammatory cytokine production in receptor activity-modifying protein 1-deficient mice. Proc Natl Acad Sci U S A. 2007 Oct 16;104(42):16702-7
• All: 2 reference(s)