Sdccag8^em1Tfur
Endonuclease-mediated Allele Detail

Summary

• Symbol: Sdccag8^em1Tfur
• Name: serologically defined colon cancer antigen 8; endonuclease-mediated mutation 1, Takahisa Furukawa
• MGI ID: MGI:7382738
• Synonyms: Sdccag8^deltaC
• Gene: Sdccag8 Location: Chr1:176642226-176848003 bp, + strand Genetic Position: Chr1, 82.66 cM, cytoband H3
• Alliance: Sdccag8^em1Tfur page

Mutation origin

• Strain of Origin: (C57BL/6 x C3H)F1

Mutation description

• Allele Type: Endonuclease-mediated (Not Applicable)
• Mutation: Nucleotide substitutions
• Mutation details: CRISPR-targeting of exon 13 inserted a stop sequence preventing translation of the C-terminal region (R537*). (J:325461)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Sdccag8 Mutation: 38 strains or lines available

References

• Original: J:325461 Tsutsumi R, et al., The carboxyl-terminal region of SDCCAG8 comprises a functional module essential for cilia formation as well as organ development and homeostasis. J Biol Chem. 2022 Feb 4;298(3):101686
• All: 1 reference(s)