Tg(Nppa-EGFP)BAC336Vmc
Transgene Detail

Summary

• Symbol: Tg(Nppa-EGFP)BAC336Vmc
• Name: transgene insertion BAC336, Vincent M Christoffels
• MGI ID: MGI:7380641
• Synonyms: BAC336-Egfp, NppaBAC336-Egfp
• Transgene: Tg(Nppa-EGFP)BAC336Vmc Location: unknown
• Alliance: Tg(Nppa-EGFP)BAC336Vmc page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Tg(Nppa-EGFP)BAC336Vmc expresses 5 genes
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	2510039O18Rik (MGI:1924284)
  mouse	Clcn6 (MGI:1347049)
  mouse	Nppa (MGI:97367)
  mouse	Nppb (MGI:97368)
  mouse	Plod1 (MGI:99907)

• Mutation details: The insert is BAC 336, from an Incyte 129/SvJ BAC library, where sequence around the start site of Nppa (cccacgccagcATGggc) was replaced with the EGFP fluorescent reporter gene. The BAC also contains the full Plod1, 2510039O18Rik, Nppb and Clcn6 gene sequences plus the 3' ends of Mfn2 and Mthfr. (J:278530)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:278530 Horsthuis T, et al., Distinct regulation of developmental and heart disease-induced atrial natriuretic factor expression by two separate distal sequences. Circ Res. 2008 Apr 11;102(7):849-59
• All: 2 reference(s)