Tns3^em4Cpar
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tns3^em4Cpar
• Name: tensin 3; endonuclease-mediated mutation 4, Carlos Parras
• MGI ID: MGI:7378793
• Synonyms: Tns3^14del
• Gene: Tns3 Location: Chr11:8381652-8614681 bp, - strand Genetic Position: Chr11, 4.99 cM
• Alliance: Tns3^em4Cpar page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: CRISPR-targeting introduced the insertion/deletion of 14 nucleotides in theTns3 gene inducing a gene frameshift in a mouse egg cell. (J:330512)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tns3 Mutation: 555 strains or lines available

References

• Original: J:330512 Merour E, et al., Transient regulation of focal adhesion via Tensin3 is required for nascent oligodendrocyte differentiation. Elife. 2022 Oct 10;11:e80273
• All: 1 reference(s)