Nlrp6^tm1Cya
Targeted Allele Detail

Summary

• Symbol: Nlrp6^tm1Cya
• Name: NLR family, pyrin domain containing 6; targeted mutation 1, Cyagen Biosciences
• MGI ID: MGI:7378458
• Synonyms: Nlrp6^-, Nlrp6^tm1cyage
• Gene: Nlrp6 Location: Chr7:140500815-140509105 bp, + strand Genetic Position: Chr7, 86.14 cM, cytoband F4
• Alliance: Nlrp6^tm1Cya page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:330378
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Not Specified
• Molecular details are not specified. (J:330378)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nlrp6 Mutation: 46 strains or lines available

References

• Original: J:330378 Fan W, et al., Estrogen receptor beta activation inhibits colitis by promoting NLRP6-mediated autophagy. Cell Rep. 2022 Oct 11;41(2):111454
• All: 1 reference(s)